Product name: Bovine Serum Albumin

Other name: BSA or "Fraction V"

CAS No: 9048-46-8

Molecular Formular: C8H9O

Application: Pharmaceutical Intermediates

What is bovine serum albumin?

Bovine serum albumin (bsa bovine serum albumin  or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.

The nickname "Fraction V" refers to albumin being the fifth fraction of the original Edwin Cohn purification methodology that made use of differential solubility characteristics of plasma proteins. By manipulating solvent concentrations, pH, salt levels, and temperature, Cohn was able to pull out successive "fractions" of blood plasma. The process was first commercialized with human albumin for medical use and later adopted for production of BSA.

what is bovine serum albumin used for?

bovine serum albumin uses in a variety of laboratory applications including its function as a protein concentration standard, its function as a cell nutrient and its ability to stabilize enzymes during restriction digest.

why is bovine serum albumin used as a standard?

bovine serum albumin bsa is used because of its stability to increase signal in assays, its lack of effect in many biochemical reactions, and its low cost, since large quantities of it can be readily purified from bovine blood, a byproduct of the cattle industry.

What is bovine serum albumin made of?
Bovine serum albumin structure and biological functions

The BSA molecule consists of 583 amino acids, bound in a single chain cross-linked with 17 cystine residues (eight disulfide bonds and one free thiol group), and has a molecular mass of 66400 Da