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CAS No:34911-55-2


Bupropion hydrochloride is a unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.

Bupropion Hydrochloride is the hydrochloride salt of an aminoketone antidepressant. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.


1.Bupropion may also be used as a treatment to manage attention deficit hyperactivity disorder (ADHD).
2. Bupropion may also be used as a prescription treatment to help people quit smoking by decreasing cravings and nicotine withdrawal effects. 
3. Bupropion may be used to prevent autumn-winter seasonal depression (seasonal affective disorder). 
4. Bupropion may also be used with other medications as a treatment for bipolar disorder (depression phase). 
5. Bupropion is used to as a prescription medical treatment for depression. It can improve mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in the brain.